The above is a picture of how a glomerulus looks. The glomerulus is one of a million filtering units that elegantly filter urine. When the tiny afferent arteriole that leads into the filter is dilated, it allows a larger amount of blood to flow into the glomerulus. Over time this damages the delicate membranes that separate the blood and protein from the fluids and minerals that will ultimately make up urine. The process of hyperfiltration occurs in kidney disease, particularly in diabetes and hypertension. Although the kidney has a regulatory mechanism to block the damaging effects of hyperfiltration, this mechanism becomes damaged over time, leading to an acceleration in kidney disease.
SGLT2 INHIBITORS PROTECT THE KIDNEY
SGLT2 INHIBITORS PROTECT THE KIDNEY
SGLT2 INHIBITORS PROTECT THE KIDNEY
The above is a picture of how a glomerulus looks. The glomerulus is one of a million filtering units that elegantly filter urine. When the tiny afferent arteriole that leads into the filter is dilated, it allows a larger amount of blood to flow into the glomerulus. Over time this damages the delicate membranes that separate the blood and protein from the fluids and minerals that will ultimately make up urine. The process of hyperfiltration occurs in kidney disease, particularly in diabetes and hypertension. Although the kidney has a regulatory mechanism to block the damaging effects of hyperfiltration, this mechanism becomes damaged over time, leading to an acceleration in kidney disease.